Pharmaceutical chemical and solvent handling skid with stainless storage tanks, dosing pumps and in-line cartridge filtration before the process
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Pharmaceutical chemicals & solvents

From drum
to process,
secured.

Every solvent, buffer and reagent that enters the plant by tanker or drum carries particulate, and every storage tank that breathes draws in airborne contamination. From the 5 µm intake filter to the sterile tank vent, the 0.5 µm pre-filter and the final 0.2 µm membrane — each stage is a barrier before the chemical reaches your process. We supply the filters that hold every one of them.

Explore the four points ↓ Talk to a pharma specialist
7days
Typical dispatch
direct from Hilden
0.2µm
Final membrane polish
PF-PES · LRV ≥ 7
USPCl. VI
Materials to USP <88> Class VI
PF-PES · PF-PT · PF-PVDF
Chemical
Compatibility · filters & seals
selected per chemical
What's at stake

One particle
fails the
batch.

Drum-borne particulate · airborne bioburden · failed integrity test · a quarantined solvent batch.

Pharmaceutical chemicals and solvents arrive ready to use — and that is exactly the risk. A tanker or drum of solvent, buffer or reagent carries rust, fibre and crystalline particulate picked up in transport and handling. Once it is in the storage tank, every fill and draw makes the tank breathe, and every unfiltered breath pulls airborne micro-organisms into the chemical. By the time it feeds the process, it has to be both particle-free and sterile.

Ultrafilter has supplied API filtration to chemical and solvent handling systems for decades — PF-PP depth filters that take the coarse particulate off incoming raw materials and pre-filter ahead of the membrane; PF-PT ePTFE (or P-BE vent filter element) sterile vents that keep each storage-tank breathing cycle sterile; and a 0.2 µm sterilising-grade membrane for the final polish before the process — PF-PES for aqueous chemicals, PF-PVDF for solvent duty, subject to a chemical-compatibility review. Because solvents and aggressive chemicals attack the wrong materials, the filter media, seals and housing are selected by chemical compatibility — consult Ultrafilter with the chemical, concentration and temperature, and we specify the materials of construction for your duty. Each element ships with its datasheet, FDA 21 CFR materials conformity and a validation guide; USP <88> Class VI for the PF-PES, PF-PT and PF-PVDF membrane elements.

Your chemical line · four filtration points

Find your point.
We spec the filter.

From the 5 µm intake filter on incoming raw materials and the sterile storage-tank vent through the 0.5 µm pre-filter to the final 0.2 µm membrane polish before the process — the full chemicals-and-solvents build-up on one live schematic. Hover a point to preview it; click to pull the risk, the exact Ultrafilter element and a one-tap quote into the read-out.

UF-CHEM-LINE · live schematic
Computing layout…
Gas · sterile vent Liquid · chemical
Point read-out
Select a point
on the line.

Each of the four markers is a real filtration duty on the chemicals-and-solvents build-up. Pick one — the read-out shows what's at risk, the exact Ultrafilter element and how to spec it.

    Materials note

    On this line the filters and seals are determined by chemical compatibility. For aqueous chemicals the final liquid membrane is PF-PES; for solvents the hydrophilic PF-PVDF sterilising-grade membrane is specified in its place after a compatibility check — PF-PVDF is tested against a list of acids, bases, solvents and oils; the ratings are listed on page 4 of its datasheet. Verify compatibility under actual process conditions before use. (PF-PT-F is hydrophobic ePTFE and serves the sterile gas / tank vent point on this same line.) The housing material is selected by the process chemical, concentration and temperature — consult Ultrafilter for the materials of construction for your duty.

    The chemicals stack

    Five product lines.
    One chemical line.

    Every filtration duty in your plant is covered by one of these product families. Elements ship with datasheet, FDA 21 CFR materials conformity and a validation guide — and are specified to your chemical compatibility.

    PF-PVDF PVDF membrane filter cartridge
    Final membrane · solvents
    PF-PVDF
    Hydrophilic PVDF membrane

    Hydrophilic PVDF membrane, specified after a chemical-compatibility review — tested against a list of acids, bases, solvents and oils (ratings on page 4 of the datasheet). LRV ≥ 7 per ASTM F838; verify compatibility under actual process conditions before use.

    PVDF · 0.1–1.0 µm →
    PF-PES PES membrane filter cartridge
    Final membrane · aqueous
    PF-PES
    Aqueous sterile membrane

    PES 0.2 µm sterilising-grade membrane for the final polish on aqueous chemicals and buffers. LRV ≥ 7 per ASTM F838 (liquid challenge); materials meet USP <88> Class VI.

    0.2 µm · LRV ≥ 7 →
    PF-PP polypropylene depth pre-filter cartridge
    Depth filter · intake & pre
    PF-PP
    Depth pre-filter

    Polypropylene depth filters — 5 µm to take the coarse particulate off incoming raw materials, and 0.5 µm to pre-filter ahead of the final membrane and protect its life.

    5 µm intake · 0.5 µm pre →
    PF-PT hydrophobic PTFE membrane filter cartridge
    Sterile tank vent
    PF-PT
    Hydrophobic vent membrane

    Hydrophobic ePTFE 0.2 µm sterile breather for the chemical storage tank — keeps every breathing cycle sterile, stays dry against solvent vapour, SIP-sterilisable and integrity-testable in place.

    ePTFE · SIP 135 °C · up to 100 cycles →
    P-BE wound borosilicate sterile vent vent filter elements
    Tank vent alternative
    P-BE
    Sterile vent filter

    Wound borosilicate vent filter, 99.99998 % related to 0.2 µm, min. 100 sterilisation cycles — the alternative sterile breather for the chemical storage tank, fitted in P-BE vent housings.

    99.99998 % related to 0.2 µm →
    Chemicals compliance
    Audit-ready.
    Documented.

    Each element carries the documentation your QA and validation teams need — and is specified to the chemical compatibility of your duty before it ever contacts the product stream.

    ASTM F838
    0.2 µm grade · LRV ≥ 7
    USP <88>
    Class VI · PES · PTFE · PVDF
    21 CFR 177–182
    FDA · membrane materials
    ISO 9001
    2015 · quality

    Filtering a new
    chemical or solvent?

    Send us the chemical, the concentration, the temperature and the flow rate — intake protection, sterile tank venting, the 0.5 µm pre-filter or the final 0.2 µm polish. We select the compatible media, seals and housing, help size the train and supply the documentation for each element.

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